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Anastrozole, Arimidex,
& Tamoxifen
Anastrozole, often called by its brand name Arimidex, is an aromatase inhibitor. When a male is undergoing testosterone replacement (TRT), the level of estradiol ( the predominant form of estrogen in men) can rise. The majority of estrogen in a man is the result of the aromatase enzyme complex converting testosterone to estradiol (E2) and Androstenedione to estrone.
Anastrozole can be used on its own to enhance GnRH release from the pituitary gland to promote FSH release to enhance fertility and endogenous testosterone production. This can be more beneficial than the increase in estrogen levels often witnessed with clomid use.
ABOUT
TESTOSTERONE REPLACEMENT THERAPY
There are a variety of testosterone formulations available. The most common and popular testosterone formulation utilized is a sustained long-acting injectable testosterone ester. Examples include Testosterone Cypionate, Testosterone Enanthate, Testosterone Propionate and Testosterone Undecanoate.
ABOUT
Enclomiphene,
Clomiphene Citrate
Enclomiphene is a selective estrogen receptor modulator (SERM). Enclomiphene stimulates the pituitary to release LH and FSH, resulting in a natural rise in testosterone production.
Clomiphene Citrate (Clomid) works similarly, and both medications can treat testosterone deficiency in men. While both medications provide a more natural approach to treating men with Low T, Enclomiphene has gained popularity given its more favorable profile to reduce estrogenic effects, more often encountered with Clomiphene usage.