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ADVANCED PEPTIDE THERAPY
Peptides are naturally occurring amino acids that are utilized as therapy for a variety of conditions. Many of the body's naturally occurring processes utilize peptides for cell signaling and to improve growth hormone secretion, wound healing, reduce inflammation, enhance energy, promote weight loss, and improve skin tone.
Peptide therapy is an adjunct and works in synergy with testosterone replacement therapy to improve treatment results and benefits.
HOW DO PEPTIDES WORK
Growth Hormone (GH), also known as somatropin, is a 191 amino acid protein that has many roles in human physiology, principal among them are skeletal muscle growth, lipolysis, and regulation of lean body mass.
Many of the peptide therapies available induce growth secretion directly from the pituitary gland or act as a growth hormone-releasing secretagogue (somatocrinin) in the hypothalamus. The gravitation toward peptide therapy to improve natural growth hormone levels compared to exogenous recombinant growth hormone has gained much attraction given their safety and efficacy to provide results.
THE FOLLOWING PEPTIDES BELOW ARE UTILIZED TO IMPROVE LEAN BODY MASS, PHYSIQUE, MUSCLE GROWTH, SKIN QUALITY, FAT LOSS, AND SLEEP QUALITY.
Ibutamoren
MK 677
Growth Hormone (GH) Secretagogue
Ibutamoren MK 677 is a novel orally active growth hormone secretagogue. Ibutamoren MK 677 has been extensively studied in humans and has profound effects on increasing natural growth hormone (GH) secretion and IGF-1 levels. In two randomized placebo-controlled studies, Ibutamoren MK 677 was found to increase fat-free mass (FFM) and improve REM sleep. The fat loss was accompanied by an increase in lean muscle mass and thigh muscle mass in patients taking Ibutamoren MK 677.
Ipamorelin
Pentapeptide
Growth Hormone (GH) Secretagogue
Ipamorelin is a potent peptide known to increase natural growth hormone secretion (secretagogue). Ipamorelin is a selective agonist of the ghrelin receptor pathway that promotes growth hormone release from the pituitary gland. Ipamorelin affects a number of anabolic processes including appetite regulation, fat processing, and energy expenditure. Ipamorelin is a peptide that has proposed clinical use to improve weight gain and raise growth hormone levels.
CJC 1295
Growth Hormone Releasing Hormone (GHRH)
CJC 1295, initially discovered in 2010, is a Growth Hormone Releasing Hormone (GHRH) that promotes Growth Hormone (GH) and IGF-1 secretion. CJC 1295 promotes protein synthesis to enhance muscle-building anabolism and performance
CJC 1295 has several benefits compared to native GHRH that include:
1) CJC 1295 is longer acting than native GHRH.
2) CJC 1295 has a longer half-life than GHRH (8-10 days for CJC 1295 vs 10-12 min for iv GHRH).
3) CJC 1295 does not impair or affect the natural pulsatile release of GH.
4) CJC 1295 has a higher binding affinity to the GHRH receptor
Tesamorelin
Egrifta Depot ®
Growth Hormone (GH) Secretagogue
Tesamorelin (Egrifta Depot ®) is a stable Growth Hormone Releasing Hormone (GHRH) that is given to treat the accumulation of body fat. Initially approved by the FDA in 2010, Tesamorelin is an effective peptide to reduce lipodystrophy over a course of 26-52 weeks of treatment. It has a molecular structure that promotes its stability in the body over native GHRH.
Sermorelin
Grow Hormone Releasing Factor 1-29 NH2- Acetate
Sermorelin stimulates a patient's own pituitary gland to increase the production and secretion of growth hormone. The advantages of Sermorelin over exogenous recombinant Growth Hormone include :
1) effects are regulated by negative feedback
2) release of hGH is more episodic and physiologic
3) preservation of the growth hormone neuroendocrine axis and stimulation of pituitary gene transcription of hGH messenger RNA
4) prevention of hypophyseal hormone failure often accompanied by aging
5) safety
Semaglutide
GLP-1 Agonist, Wegovy®, Ozempic ®
Semaglutide mimics a hormone naturally produced in the body called GLP-1 (Glucagon-Like Peptide). GLP-1 is a hormone that acts on the brain to help regulate a person's desire to eat, slow down gastric emptying, and suppress appetite. The end result of using semaglutide is a significant reduction in body weight and improved glycemic control.
1) Lose up to 12% of your body weight by week 28
2) Visible results as soon as 8 weeks
3) FDA approved for weight loss
4) Safe & Effective.
