Sperm Function, Fertility and Testosterone

Keywords: Fertility, Sperm Function, sperm banking, infertility, Clomid, HCG, Anastrozole,

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Many patients will ask “How long does it take after stopping testosterone replacement therapy for my fertility to return to normal?” The answer depends on several factors. First, how long has the patient been on testosterone replacement therapy (TRT). A longer duration of TRT, higher BMI and a higher dose of TRT can suppress sperm production more so than a shorter course or lower dosage of testosterone therapy. Second, is patient age. Men who are older and who are undergoing TRT can expect a longer sperm recovery time compared to a younger male. Third, during TRT the use of HCG can maintain spermatogenesis and testicular volume ( ie. prevent testicular shrinkage) . Using HCG in combination with testosterone can reduce the chance of infertility during TRT.

After a man starts testosterone replacement therapy, it takes approximately 2.7 months for the total sperm count to be reduced. After testosterone therapy cessation, it can often take 6 months before the total sperm count returns to normal. Spontaneous recovery of fertility is common after stopping testosterone therapy, yet this process can be expedited.

To expedite sperm recovery during or after testosterone therapy, men have several medication options that include: