How a man feels on Testosterone Therapy


1) Improvement in Sex Drive, Energy and Muscle Mass / Strength

2) Social Energy and Motivation to complete tasks

3) Improvement in fat free mass, reduction in waist circumference


Keywords: What does testosterone do to me, What will I expect on Testosterone Therapy, What will I feel on TRT, High dose Testosterone Therapy, Weight Loss, Muscle Size, Muscle Strength, Mood, Behavior, Focus, Energy.


Men can feel the effects of testosterone replacement therapy (TRT) in as little as 2-4 weeks. In most men effects of TRT are felt within 3 months. The most commonly improved symptoms enhanced by TRT include improvements in energy, sex drive, muscle size, strength, fat loss and improved mood. In a clinical study by Straftis et. al., Sex, Energy, Well- Being and Low Testosterone: An Exploratory Survey of U.S. Men’s Experiences on Prescription Testosterone, men on TRT were asked the following questions:

Since taking prescription testosterone, have you noticed any changes in your motivation at school/work?”

98% of men found testosterone replacement to have a positive improvement in their ability to focus and motivation for work tasks. While other studies confirm testosterone to be linked to dominance motivation and status striving, a performance enhancing effect, testosterone heightens motivation to complete tasks.

Describe any changes you have noticed in your family life, since taking testosterone”

58.1 % found improvement in social energy, energy used for quality of life activities and family activities.

What did you perceive as the benefits of testosterone?

Most men in the study found a benefit with testosterone replacement, with benefits mostly focused around energy, performance, well-being, fat loss, muscle growth and an overall feeling of well-being.


In survey of 110 men published by Gilbert K et. al., the major symptoms experienced by men with Low T most notably include low energy, fatigue and naps after work, low sex drive, weak erections, and decreased strength. Of the perceived benefits from testosterone replacement therapy were improved sexual function and desire, increased daily energy and well-being.


High Dose Testosterone

For men who receive high doses of testosterone significant increases in muscle arm size, triceps size and quadricep size has been reported in clinical studies. A study published in the New England Journal of Medicine, The Effects of Supraphysiologic Doses of Testosterone on Muscle Size and Strength in Normal Men by Bhasin et.al., found men who were given 600mg of testosterone enanthate weekly paired with an exercise routine were found to have a significant increase in fat free mass, increase in diameter of quadriceps and arms and improvement in strength ( measured by an increase in bench press weight by 22% percent and squatting exercise increase by 38%). There were no changes in mood, behavior, or aggressiveness in men who were provided supraphysiological doses of testosterone. Total testosterone measurements in male subjects after administration of 600mg of testosterone enanthate were 2828 +/- without exercise and 3244 +/- with an exercise routine. No immediate toxicities were observed during the 10-week study duration, yet long term studies are necessary to provide reliable safety data.

While this study provided insights into the beneficial effects of supraphysiological dosages of testosterone and safety, it is well known that performance and bodybuilding athletes take even higher dosages of testosterone. The term “stacking” is often utilized by athletes who use multiple androgenic steroid medications to achieve a desired performance outcome and/or physique. Stacking anabolic steroids can achieve supraphysiological levels of testosterone.


Finally, there was no documented cases of aggressive behavior or tendencies with high dose testosterone usage. This is supported in other clinical studies that aggression is not correlated with wither testosterone levels or having used testosterone therapy.

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